There was a single sex women's college in Columbia, MO when I attended Mizzou. I think those girls found ways to talk to boys.
Like any scenario its upbringing that determines whether such a school works. And does the corollary apply ? Are prep school boys disadvantaged by not knowing how to talk to girls ?
Learning to talk to the opposite sex is not something always learned in regular schools either.
Brighton College head says single-sex schools harm girls as 'they can't talk to boys' | Daily Mail Online